Chemical fixation of biological samples for light and electron microscopies is required to halt biochemical reactions, prevent autolysis, stabilize macromolecules, preserve delicate morphologies and reduce artefacts which may be induced during other treatments such as dehydration. Besides these general objectives of all fixatives there are also some selected for performing specific functions, such as staining individual organelles or structures. Read on for a list of the more popular fixatives, their functions and other benefits.

Read the Kirsch Note here